Article Summary
曾 艾,张 琴,刘 炜,何 梅,王 聪.超声联合钼靶X线对直径小于1 cm的乳腺癌诊断价值分析[J].现代生物医学进展英文版,2019,19(11):2144-2147.
超声联合钼靶X线对直径小于1 cm的乳腺癌诊断价值分析
The Diagnostic Value of Ultrasound Combined with Mammography X-ray for Breast Cancer Less than 1 cm in Diameter
Received:November 16, 2018  Revised:December 12, 2018
DOI:10.13241/j.cnki.pmb.2019.11.030
中文关键词: 彩色多普勒超声  钼靶X线  肿瘤直径  乳腺癌  诊断
英文关键词: Color doppler ultrasound  Molybdenum target X-ray  Tumor diameter  Breast cancer  Diagnosis
基金项目:新疆维吾尔自治区自然科学基金项目(2016D01C215)
Author NameAffiliationE-mail
ZENG Ai Ultrasound Department, The Sixth Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, 830002, China zengai1981@163.com 
ZHANG Qin Ultrasound Department, The People's Hospital of Shihezi, Shihezi, Xinjiang, 832000, China  
LIU Wei Lymphoma and Breast Cancer Internal Medicine, Tumor Hospital of Xinjiang Medical University, Urumqi, Xinjiang, 830002, China  
HE Mei Ultrasound Department, The Sixth Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, 830002, China  
WANG Cong Ultrasound Department, The Sixth Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, 830002, China  
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中文摘要:
      摘要 目的:探讨超声联合钼靶X线对直径小于1 cm的乳腺癌诊断价值。方法:选择我院2012年1月至2017年12月收治的66例乳腺疾病患者,所有患者术前均经钼靶X线及彩色多普勒超声检查,分析其病理结果,分析钼靶X线、彩色多普勒超声及二者联合对乳腺肿块的检查结果(边缘毛刺征、血管、淋巴结、微小钙化),比较其对乳腺癌的灵敏度、特异度、准确度、阳性预测值及阴性预测值。结果:66例患者中,经病理检查发现恶性肿瘤34例,良性肿瘤32例。与病理检测相比,彩色多普勒超声联合钼靶X线对乳腺肿块的良恶性检出率无差异性(P>0.05),而彩色多普勒超声,钼靶X线的良恶性检出率均显著降低(P<0.05)。彩色多普勒超声与钼靶X线良恶性检出率对比无差异(P>0.05),但均低于彩色多普勒超声联合钼靶X线的检出率(P<0.05)。彩色多普勒超声与钼靶X线对乳腺癌的边缘毛刺征的检出率对比无统计学意义(P>0.05);彩色多普勒超声对血管和淋巴结的检出率明显高于钼靶X线,而微小钙化的检出率明显低于钼靶X线,对比差异有统计学意义(P<0.05)。彩色多普勒超声联合钼靶X线的灵敏度、特异度、准确度、阳性预测值及阴性预测值均明显高于彩色多普勒超声及钼靶X线(P<0.05),钼靶X线及彩色多普勒超声间对比无统计学意义(P>0.05)。结论:彩色多普勒超声与钼靶X线对直径小于1 cm乳腺癌的诊断各有优势,二者联合应用的诊断价值优于单一诊断方法。
英文摘要:
      ABSTRACT Objective: To investigate the diagnostic value of ultrasound combined with mammography x-ray for breast cancer less than 1cm in diameter. Methods: 66 cases with breast disease patient from Jan. 2012 to Dec. 2017 in our hospital were chosen, who were performed by molybdenum target X-ray and color doppler ultrasonography before operation, the pathologic result were analyzed, the breast masses results(marginal burr, blood vessels, lymph node, microcalcification) of molybdenum target X-ray, color doppler ultrasound and combination of the two methods were analyzed. The sensitivity, specificity, accuracy, positive predictive value and negative predic- tive value of molybdenum target X-ray, color doppler ultrasound and combination of the two methods were compared. Results: Among the 66 cases, 34 were malignant and 32 were benign. Compared with pathological examination, the detection rate of benign and malig- nant by color doppler ultrasound combined with molybdenum target X-ray had no difference(P>0.05), but the detection rate of benign and malignant breast by color doppler ultrasound and molybdenum target X-ray were significantly lower(P<0.05). There was no signifi- cant difference between color doppler ultrasound and molybdenum target X-ray(P>0.05), but the detection rate was lower than that of color doppler ultrasound combined with molybdenum target X-ray(P<0.05). There was no significant difference between color doppler ultrasound and molybdenum target X-ray in detecting marginal burr of breast cancer(P>0.05). The detection rate of blood vessels and lymph nodes by color doppler ultrasound was significantly higher than that by molybdenum target X-ray, while the detection rate of mi- crocalcification was significantly lower than that by molybdenum target X-ray(P<0.05). The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of color doppler ultrasound combined with molybdenum target X-ray were significantly higher than those of color doppler ultrasound and molybdenum target X-ray(P<0.05). There was no significant difference between molyb- denum target X-ray and color doppler ultrasound (P>0.05). Conclusion: Both color doppler ultrasound and molybdenum target X-ray had advantages in the diagnosis of breast cancer with diameter less than 1 cm, while the combined diagnosis was superior to the single diagnosis.
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