Article Summary
李 梅,汪小五,刘 艳,吴 亚,高 勇.新型冠状病毒肺炎患者血清SAA、ESR、CRP检测结果分析[J].现代生物医学进展英文版,2020,(10):1949-1951.
新型冠状病毒肺炎患者血清SAA、ESR、CRP检测结果分析
Analysis of Serum Amyloid A, Serum Sedimentation and C-reactive Protein in COVID-19 Patients
Received:March 30, 2020  Revised:April 23, 2020
DOI:10.13241/j.cnki.pmb.2020.10.033
中文关键词: ESR  CRP  SAA  COVID-19
英文关键词: Erythrocyte sedimentation rate  C-reactive protein  Serum amylase A  COVID-19
基金项目:江苏省自然科学基金项目(2016C256)
Author NameAffiliationE-mail
LI Mei Department of laboratory, the second people's Hospital, Fuyang City, Anhui Province, Fuyang, Anhui, 236000, China wangxiaomeng970@163.com 
WANG Xiao-wu Department of laboratory, the second people's Hospital, Fuyang City, Anhui Province, Fuyang, Anhui, 236000, China  
LIU Yan Department of laboratory, the second people's Hospital, Fuyang City, Anhui Province, Fuyang, Anhui, 236000, China  
WU Ya Department of respiratory, Fuyang hospital, Anhui Medical University, Fuyang, Anhui, 236000, China  
GAO Yong Department of laboratory, the second people's Hospital, Fuyang City, Anhui Province, Fuyang, Anhui, 236000, China  
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中文摘要:
      摘要 目的:分析新型冠状病毒肺炎(COVID-19)患者血清淀粉样蛋白A(SAA)、血沉ESR(ESR)、C-反应蛋白CRP(CRP)的临床价值。方法:以我院2020年1月至2020年2月确诊的COVID-19患者51例为实验组:其中重症患者21例,轻症患者30例,选取非感染患者30例为对照组。分析新型冠状病毒肺炎(COVID-19)患者血清SAA、ESR、CRP水平以及临床价值。结果:实验组SAA、ESR、CRP水平高于对照组(P<0.05);重症组SAA、ESR、CRP水平高于轻症组(P<0.05),由ROC曲线得知SAA、ESR、CRP预测COVID-19的AUC小于三者联合预测的AUC。结论:COVID-19的SAA、ESR、CRP水平会升高,三者联合预测为疾病评估、预测疾病发展的提供依据,值得临床进一步推广应用。
英文摘要:
      ABSTRACT Objective: To analyze of the clinical values of serum amyloid A (SAA), serum sedimentation (ESR) and c-reactive protein (CRP) in sera from COVID-19 patients. Methods: 51 patients with COVID-19 diagnosed in our hospital from January 2020 to February 2020 were involved as the experimental group. Among them, 21 severe patients, 30 mild patients, and 30 non-infected patients were treated as the control group. The levels of SAA, ESR and CRP were detected sera from COVID-19 patients. Results: The levels of SAA, ESR and CRP in the experimental group were higher than those in the control group (P<0.05).The levels of SAA, ESR and CRP in the severe group were higher than that in the mild group (P<0.05). According to the ROC curve, the AUC of SAA, ESR and CRP in the prediction of COVID-19 was lower than that in the combined detection of the three. Conclusion: The serum levels of SAA, ESR and CRP of COVID-19 will increase. The Combined detection of SAA, ESR and CRP can improve the accuracy of diagnosis of COVID-19. It provides the basis for clinical prediction and treatment to evaluate the disease and predict the development of the disease.
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