| 张召菊,唐桂娥,高兰翠,桑学梅,杜丹丽,卫 兵.阴式手术与开腹手术对子宫良性肿瘤患者炎性应激反应、盆底功能及性生活质量的影响[J].现代生物医学进展英文版,2021,(7):1279-1282. |
| 阴式手术与开腹手术对子宫良性肿瘤患者炎性应激反应、盆底功能及性生活质量的影响 |
| Effects of Vaginal and Open Surgery on Inflammatory Stress Response, Pelvic Floor Function and Sexual Quality of Life in Patients with Uterine Benign Tumor |
| Received:September 24, 2020 Revised:October 18, 2020 |
| DOI：10.13241/j.cnki.pmb.2021.07.017 |
| 中文关键词: 阴式手术 开腹手术 子宫良性肿瘤 炎性应激反应 盆底功能 |
| 英文关键词: Vaginal operation Laparotomy Uterine benign tumor Inflammatory stress response Pelvic floor function |
| 基金项目:国家自然科学基金项目（81101548）；安徽省公益性研究联动计划项目（1604f0705031） |
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| 中文摘要: |
| 摘要 目的：探讨阴式手术与开腹手术对子宫良性肿瘤患者盆底功能、炎性应激反应及性生活质量的影响。方法：回顾性分析我院自2017年3月~2019年1月期间收治的子宫良性肿瘤患者78例的临床资料，上述患者根据手术方案的不同分为A组（n=38，给予开腹手术治疗）和B组（n=40，给予阴式手术治疗），对比两组患者围术期指标、炎性应激指标[白介素-6（IL-6）、C反应蛋白（CRP）、皮质醇（Cor）]、盆底功能障碍发生率、并发症发生率及性生活质量。结果：B组术后排气时间、手术时间、住院时间、术后下床时间短于A组，术中出血量少于A组（P<0.05）。两组术后2 d 的IL-6、CRP、Cor均升高，但B组低于A组（P<0.05）。B组患者盆底功能障碍发生率为12.50%（5/40），低于A组的36.84%（14/38）（P<0.05）。两组患者术后1年女性性功能指数量表（FSFI）评分均较术前增加，且B组高于A组（P<0.05）。B组术后并发症发生率低于A组（P<0.05）。结论：与开腹手术相比，阴式手术应用于子宫良性肿瘤患者，可有效改善围术期指标、炎性应激反应、盆底功能及性生活质量，减少并发症发生率。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the Effects of vaginal and open surgery on pelvic floor function, inflammatory stress response and sexual quality of life in patients with uterine benign tumor. Methods: The clinical data of 78 patients with uterine benign tumor from March 2017 to January 2019 were analyzed retrospectively, the patients were divided into group A (n=38, treatment by open surgery) and group B (n=40, treatment by vaginal surgery) according to the different operative plans, the indexes of perioperative period, inflammatory stress indexes [Interleukin-6 (IL-6), C-reactive protein (CRP), Cortisol（Cor）], pelvic floor dysfunction, complications and sexual quality of life were compared between the two groups. Results: The time of exhaust, operation, hospitalization and getting out of bed in group B were shorter than that in group A, and the amount of bleeding was less than that in group A (P<0.05). The levels of IL-6, CRP and cor were all increased in two groups, but the level in group B was lower than that in group A (P<0.05). The incidence of pelvic floor dysfunction in group B was 12.50% (5 / 40), lower than 36.84% (14 / 38) in group A (P<0.05). The score of Female sexual function index scale（FSFI）in the two groups was higher than that before operation, and the score in group B was higher than that in group A (P<0.05). The incidence of postoperative complications in group B was lower than that in group A(P<0.05). Conclusion: Compared with laparotomy, vaginal surgery can effectively improve the perioperative indicators, inflammatory stress response, pelvic floor function and sexual quality of life, and reduce the incidence of complications. |
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