| 崔志梅,侯 敏,朱欧鸰,王秀民,刘恒亮.耳穴埋豆联合柴术汤对肝郁脾虚型2型糖尿病伴抑郁患者糖代谢、炎症因子和HPA轴的影响[J].现代生物医学进展英文版,2024,(19):3667-3669. |
| 耳穴埋豆联合柴术汤对肝郁脾虚型2型糖尿病伴抑郁患者糖代谢、炎症因子和HPA轴的影响 |
| Effects of Ear Point Burying Beans Combined with Chaishu Decoction on Glucose Metabolism, Inflammatory Factors and HPA Axis in Patients with Type 2 Diabetes Mellitus with Depression of Liver Depression and Spleen Deficiency Type |
| Received:February 11, 2024 Revised:March 07, 2024 |
| DOI：10.13241/j.cnki.pmb.2024.19.016 |
| 中文关键词: 耳穴埋豆 柴术汤 肝郁脾虚型 2型糖尿病伴抑郁 糖代谢 炎症因子 HPA轴 |
| 英文关键词: Ear point burying beans Chaishu decoction Liver depression and spleen deficiency type Type 2 diabetes mellitus with depression Glucose metabolism Inflammatory factors HPA axis |
| 基金项目:河北省中医药管理局科研计划项目（2020339） |
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| 中文摘要: |
| 摘要 目的：观察耳穴埋豆联合柴术汤对肝郁脾虚型2型糖尿病（T2DM）伴抑郁患者糖代谢、炎症因子和下丘脑-垂体-肾上腺（HPA）轴的影响。方法：采用随机数字表法将2020年8月~2023年8月期间于我院就诊的96例T2DM伴抑郁患者分为对照组（48例，柴术汤治疗）和研究组（48例，对照组的基础上接受耳穴埋豆治疗）。对比两组糖代谢、炎症因子和HPA轴变化情况。结果：两组治疗后血糖指标、炎症因子水平、HPA轴相关指标下降，且研究组低于对照组同时间点（P<0.05）。结论：耳穴埋豆联合柴术汤可有效改善肝郁脾虚型T2DM伴抑郁患者糖代谢、炎症因子和HPA轴相关指标。 |
| 英文摘要: |
| ABSTRACT Objective: To observe the effects of ear point burying beans combined with chaishu decoction on glucose metabolism, inflammatory factors and hypothalamic-pituitary-adrenal (HPA) axis in patients with type 2 diabetes mellitus (T2DM) with depression of liver depression and spleen deficiency type. Methods: 96 T2DM patients with depression who were treated in our hospital from August 2020 to August 2023 were selected as control group (48 cases, chaishu decoction treatment) and study group (48 cases, control group was treated with ear point burying beans on the basis of control group) by random number table method.The changes in glucose metabolism, inflammatory factors and HPA axis were compared between the two groups. Results: Blood glucose index, inflammatory factor level and HPA axis related index decreased after treatment in both groups, and the study group was lower than the control group (P<0.05). Conclusion: Ear point burying beans combined with chaishu decoction can effectively improve glucose metabolism, inflammatory factors and HPA axis relate indexes in T2DM patients with depression of liver depression and spleen deficiency. |
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