| 张 力,胡凯峰,高 原,张 旭,李江涛.对比分析小肠内排列术与腹腔镜下肠粘连松解术治疗粘连性肠梗阻患者效果分析[J].现代生物医学进展英文版,2024,(19):3731-3735. |
| 对比分析小肠内排列术与腹腔镜下肠粘连松解术治疗粘连性肠梗阻患者效果分析 |
| Comparative Analysis of the Effect of Small Intestinal Arrangement and Laparoscopic Intestinal Adhesiolysis in Patients with Adhesive Ileus |
| Received:April 06, 2024 Revised:April 28, 2024 |
| DOI：10.13241/j.cnki.pmb.2024.19.034 |
| 中文关键词: 粘连性肠梗阻 小肠内排列术 腹腔镜下肠粘连松解术 胃肠道功能 氧化应激 |
| 英文关键词: Adhesive ileus Intraintestinal arrangement Laparoscopic intestinal adhesiolysis Gastrointestinal function Oxidative stress |
| 基金项目:陕西省自然科学基金项目（S2021 JCYB-18） |
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| 中文摘要: |
| 摘要 目的：对比分析小肠内排列术与腹腔镜下肠粘连松解术治疗粘连性肠梗阻患者疗效及对胃肠道功能、氧化应激指标的影响。方法：选择我院自2021年1月至2023年10月收治的106例粘连性肠梗阻患者作为研究对象，随机分为A组和B组，各53例。A组予以小肠内排列术治疗，B组予以腹腔镜下肠粘连松解术治疗。比较两组手术时间、术中出血量、导尿管拔除时间、术后离床活动时间、术后住院时间、术后恢复肠蠕动时间、术后恢复普通饮食时间、术中及术后并发症发生率、手术前后的活性氧簇、超氧化物歧化酶、丙二醛水平及临床有效率。结果：两组手术时间、术中出血量相当（P＞0.05）；对比A组的导尿管拔除时间、术后离床活动时间、术后住院时间，B组均更短（P＜0.05）；对比A组的术后恢复肠蠕动时间、术后恢复普通饮食时间，B组均更短（P＜0.05）；B组术中及术后并发症发生率为3.77%，低于A组的16.98%（P＜0.05）；B组术后血清活性氧簇、丙二醛水平均更低，超氧化物歧化酶水平更高，与A组比较有差异（P＜0.05）；两组临床有效率相当（P＞0.05）。结论：小肠内排列术与腹腔镜下肠粘连松解术治疗粘连性肠梗阻患者的疗效均较好，后者的术后恢复过程更快，在促进胃肠道功能恢复和减轻氧化应激上具有优势，安全性更高。 |
| 英文摘要: |
| ABSTRACT Objective: To comparative analysis of the small intestine internal arrangement with laparoscopic treatment of intestinal adhesion release adhesion sex intestinal obstruction in patients with curative effect and the influences on the targets of gastrointestinal function,and oxidative stress. Methods: Select our hospital from January 2021 to October 2023 were 106 adhesion sex intestinal obstruction patients as the research object, were randomly divided into group A and group B, 53 cases. For the treatment of group A will be arranged within the small intestine, group B for the treatment of laparoscopic intestinal adhesion release. Compare two groups of operation time, intraoperative blood loss, postoperative catheter time, postoperative activities from the bed time, postoperative hospital stay, postoperative recovery of intestinal peristalsis, postoperative recovery time ordinary diet time, intraoperative and postoperative complications, before and after operation of reactive oxygen species, superoxide dismutase(sod), malondialdehyde level and clinical effectiveness. Results: The surgical time and intraoperative blood loss were comparable between the two groups(P>0.05); Compared with group A, group B had shorter catheter removal time, postoperative time to move out of bed, and postoperative hospital stay(P<0.05); Compared with group A, group B had shorter postoperative recovery time for intestinal peristalsis and normal diet (P<0.05); The incidence of intraoperative and postoperative complications in group B was 3.77 %, lower than group A's 16.98%(P<0.05); The postoperative serum levels of reactive oxygen species and malondialdehyde were lower in group B, and the levels of superoxide dismutase were higher, which was different from group A(P<0.05); The clinical effective rates of the two groups were equivalent (P>0.05). Conclusion: Small intestine lined with laparoscopic operation for the treatment of intestinal adhesion release adhesion sex intestinal obstruction in patients with curative effect is better, faster postoperative recovery process of the latter, in promoting recovery of gastrointestinal function and reduce the oxidative stress on the advantages, security is higher. |
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