| .神经肌肉刺激对慢性阻塞性肺疾病急性加重期患者肺功能、
躯体症状及躯体活动能力的影响[J].现代生物医学进展英文版,2024,(24):4791-4793. |
| 神经肌肉刺激对慢性阻塞性肺疾病急性加重期患者肺功能、
躯体症状及躯体活动能力的影响 |
| Effects of Neuromuscular Stimulation on Pulmonary Function, Somatic Symptoms and Physical Activity Ability in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease |
| Received:August 09, 2024 Revised:September 01, 2024 |
| DOI：doi: 10.13241/j.cnki.pmb.2024.24.048 |
| 中文关键词: 神经肌肉刺激 慢性阻塞性肺疾病 急性加重期 肺功能 躯体症状 躯体活动能力 |
| 英文关键词: Neuromuscular stimulation Chronic obstructive pulmonary disease Acute exacerbation Pulmonary function Somatic symptoms Physical activity ability |
| 基金项目:河北省卫健委医学科学研究课题（20210703）；河北省医学科学研究课题计划项目(20211187) |
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| 中文摘要: |
| 摘要 目的：探讨神经肌肉刺激对慢性阻塞性肺疾病急性加重期（AECOPD）患者肺功能、躯体症状及躯体活动能力的影响。方法：92例AECOPD患者分为对照组（呼吸训练干预，n=46）和试验组（对照组的基础上接受神经肌肉刺激干预，n=46）。观察两组肺功能指标[用力肺活量占预计值百分比（FVC% pred）、第1秒用力呼气容积（FEV1）/用力肺活量（FVC）]、躯体症状[改良版英国医学研究会呼吸困难量表（mMRC）、圣乔治呼吸问卷（SGRQ）]及躯体活动能力[6分钟步行实验（6MWT）、四肢骨骼肌质量指数（ASMI）]变化情况。结果：干预 8周后，两组FVC% pred、FEV1/FVC升高，且试验组高于对照组同期（P＜0.05）。干预 8周后，两组SGRQ、mMRC评分下降，且试验组低于对照组同期（P＜0.05）。干预 8周后，两组6MWT、ASMI升高，且试验组高于对照组同期（P＜0.05）。结论：神经肌肉刺激用于AECOPD患者，可有效改善肺功能和躯体症状，提高躯体活动能力。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the effects of neuromuscular stimulation on pulmonary function, somatic symptoms and physical activity ability in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods: 92 patients with AECOPD were divided into control group (respiratory training intervention, n=46) and experimental group (neuromuscular stimulation intervention on the basis of control group, n=46) by random number table method. The changes of pulmonary function indexes [forced vital capacity as a percentage of predicted value (FVC%pred), forced expiratory volume in the first second (FEV1)/forced vital capacity (FVC)], somatic symptoms [modified British medical research council dyspnea scale(mMRC), St. George's respiratory questionnaire (SGRQ)] and physical activity ability [6-minute walk test (6MWT), appendicular skeletal mass index (ASMI)] were observed in two groups. Results: 8 weeks after intervention, the FVC%pred and FEV1/FVC in two groups increased, with the experimental group being higher than the control group at the same time(P<0.05). 8 weeks after intervention, the scores of SGRQ and mMRC in two groups decreased, with the experimental group being lower than the control group at the same time(P<0.05). 8 weeks after intervention, the 6MWT and ASMI increased in two groups, with the experimental group being higher than the control group at the same time(P<0.05). Conclusion:Neuromuscular stimulation can effectively improve pulmonary function and somatic symptoms, and improve physical activity ability in patients with AECOPD. |
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