| Objective:To explore the risk factors of pulmonary embolism (PE) in pregnant women and clinical value of biological index changes.Methods:From January 2021 to December 2024,21 pregnant women diagnosed with PE (case group) and 63 matched control pregnant women (control group) in the obstetrics department of Guizhou Provincial People ''s Hospital were selected as the research objects.The differences of risk factors and biological indicators between the two groups were compared,and the possible related factors were analyzed.Results:The results of univariate analysis showed that there were significant differences in chest tightness, chest pain, dyspnea, edema of both lower limbs, premature delivery, multiple pregnancy, pneumonia, hypertension, heart disease and postpartum hemorrhage between the two groups (P<0.05), and the proportion of the above symptoms in the case group was significantly higher than that in the control group.Logistics regression analysis showed that heart disease was an independent risk factor for PE (P<0.05).There were significant differences in hemoglobin (HB), high density lipoprotein cholesterol(HDL-C),total protein,albumin and globulin between the case group and the control group (P<0.05), and HB, HDL-C,total protein,albumin and globulin in the case group were significantly lower than those in the control group,While no significant difference in other indicators(P>0.05).Conclusion:The prevention and treatment of maternal PE should pay attention to the identification of high-risk factors, especially high-risk pregnant women with heart disease, hypoproteinemia and hyperlipidemia. Lower HB, HDL-C, total protein, albumin and globulin may be closely related to the occurrence of maternal PE, which is expected to be a predictor of maternal PE. |
