Article Summary
159例小儿肠系膜淋巴结炎的中药处方用药规律分析
Analysis of the medication pattern of traditional chinese medicine prescriptions for 159 cases of pediatric mesenteric lymphadenitis
投稿时间:2025-04-28  修订日期:2025-04-28
DOI:
中文关键词: 小儿  肠系膜淋巴结炎  中药  用药规律
英文关键词: Children  Mesenteric lymphadenitis  Traditional chinese medicine  Medication pattern
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作者单位邮编
杨雨婷* 重庆医科大学附属儿童医院中医科/国家儿童健康与疾病临床医学研究中心/儿童发育疾病研究教育部重点实验室/重庆医科大学附属儿童医院大数据工程中心 400014
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中文摘要:
      目的:分析小儿肠系膜淋巴结炎的中药用药规律,为临床治疗该病提供用药参考。方法:收集2020年1月-2024年3月重庆医科大学附属儿童医院中医科门诊诊断为小儿肠系膜淋巴结炎的口服中药处方共159份。运用Excel软件创建用药数据库,应用古今医案云平台、SPSS软件分析高频中药应用情况、中药四气、五味、归经以及关联分析、聚类分析。结果:药物频次排前10的分别是甘草、山楂、陈皮、延胡索、麦芽、白芍、厚朴、茯苓、白术、连翘;药性居前3位依次为温、平、寒;药味居前3位的为甘、辛、苦;药物归经居前3位的为脾、肺、胃;关联规则分析得出核心药物4组;聚类分析将高频中药分为4个有效类方群。结论:中医治疗小儿肠系膜淋巴结炎;关联规则分析得出了核心药物组合,包括甘草、山楂、陈皮等;聚类分析将高频中药分为四类方群,以理气健脾、健脾祛湿、清热解毒、行气活血为治法,为临床合理应用中药治疗小儿肠系膜淋巴结炎提供参考依据。
英文摘要:
      Objective: To analyze the medication pattern of traditional chinese medicine for pediatric mesenteric lymphadenitis, and to provide medication reference for clinical treatment of this disease. Methods: A total of 159 traditional chinese medicine prescriptions who were diagnosed with pediatric mesenteric lymphadenitis in the outpatient department of the Traditional Chinese Medicine Department of Chongqing Medical University Affiliated Children''s Hospital from January 2020 to March 2024 were collected. A medication database was created by Excel software, and the high-frequency application of traditional chinese medicine, four qi of traditional chinese medicine, five flavors, meridian tropism, correlation analysis, and cluster analysis were analyzed by ancient and modern medical case cloud platform and SPSS software. Results: The top 10 drugs in terms of frequency were licorice, hawthorn, tangerine peel, corydalis yanhusuo, malt, white peony, magnolia officinalis, poria cocos, atractylodes macrocephala, and forsythia suspensa. The top three medicinal properties were warm, calm, and cold. The top three medicinal flavors were sweet, spicy, and bitter. The top three drugs classified by meridian were spleen, lung, and stomach. Association rule analysis identified four groups of core drugs. Cluster analysis divides high-frequency traditional Chinese medicine into four effective prescription groups. Conclusion: Traditional chinese medicine treatment for pediatric mesenteric lymphadenitis. Association rule analysis has identified core drug combinations, including licorice, hawthorn, tangerine peel, etc; Cluster analysis divides high-frequency traditional chinese medicine into four groups of prescriptions, with the treatment methods of regulating qi and strengthening spleen, strengthening spleen and eliminating dampness, clearing heat and detoxifying, and promoting qi and blood circulation, providing reference for the rational application of traditional chinese medicine in the treatment of pediatric mesenteric lymphadenitis in clinical practice.
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