Abstract There was a close relationship between microvascular invasion (MVI) and the therapeutic efficacy and prognosis of hepatocellular carcinoma. With the continuous development of imaging examination methods, multimodal magnetic resonance imaging (MRI) was a non-invasive and quantitative examination method that combines multiple imaging modes, including magnetic resonance T1/T2 weighted imaging (T1/T2WI), functional MRI [diffusion-weighted imaging (DWI), intravoxel incoherent motion (IVIM) and diffusion-kurtosis imaging (DKI)], dynamic contrast-enhanced MRI (DCE-MRI), hepatobiliary phase imaging (HBP), etc, it can obtain various imaging parameters and provide more comprehensive and accurate diagnostic information for clinicians, it has been widely used in the diagnosis and grading, efficacy evaluation, prognosis, and MVI prediction of hepatocellular carcinoma. Based on this, this article reviews the relevant literature on the application of multimodal MRI in MVI of hepatocellular carcinoma in recent years, and summarizes the research status and progress of multimodal MRI in predicting hepatocellular carcinoma MVI, the aim was to further analyze the challenges of multimodal MRI in the application of hepatocellular carcinoma MVI, promote the clinical application of predicting hepatocellular carcinoma MVI, and improve the accuracy of predicting of hepatocellular carcinoma MVI. |