| 王丽晔李峰△ 宋月晗马佳美李思耐关冰河.Ghrelin 发现和结构的研究现状[J].,2011,11(18):3589-3591 |
| Ghrelin 发现和结构的研究现状 |
| The discovery and structure of Ghrelin |
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| DOI： |
| 中文关键词: Ghrelin 脑肠肽 结构 |
| 英文关键词: Ghrelin Braingut petide Structure |
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| 中文摘要: |
| Ghrelin 是生长激素促分泌素受体(growth hormone secretagogue receptor，GHSR)的内源性配体，是1999 年由Kojima 等[ ]人
从大鼠胃组织中发现的含28 个氨基酸的多肽，主要由胃黏膜泌酸腺X／A 样细胞分泌并通过与其特异性受体结合而产生多种生
物学效应。本文总结了近几年的文章，旨在通过对Ghrelin 的发现和结构的介绍，为以后的相关研究奠定基础。 |
| 英文摘要: |
| Ghrelin is the endogenic ligand of growth hormone secretagogue receptor (GHSR), it was detected in stomach of
mouse by Kojima in 1999 for the first time, it is a polypeptide which has 28 amino acids. Ghrelin is excreted by X/A cells in stomach mucous
membrane secretory and do the deed through combing with its specificity antibody. The article summarizes many papers which appeard
in recent years and wants to lay the foundation of correlational investigation. |
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