文章摘要
王燕1 张颖2 张毅1△ 王伟1 刘薇1 周静1.脉搏波传导速度检测在评价高血压病患者大动脉弹性中的应用 与影响因素分析[J].,2012,12(22):4307-4311
脉搏波传导速度检测在评价高血压病患者大动脉弹性中的应用 与影响因素分析
Application Evaluation and Affect Factor of Pulse Wave Velocity LargeArterial Elasticity in Hypertensive Patients
  
DOI:
中文关键词: 脉搏波传导速度  高血压  大动脉弹性  影响因素
英文关键词: Pulse wave velocity  Hypertension  Arterial elasticity  Affect factor
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作者单位
王燕1 张颖2 张毅1△ 王伟1 刘薇1 周静1 青岛大学医学院附属医院健康体检中心 
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中文摘要:
      目的:探讨脉搏波传导速度(PWV)检测在评估高血压病患者大动脉弹性中的应用价值与影响因素分析。方法:采用分层整 体抽样法随机抽取高血压病患者2178 例,同时抽取非高血压2182 人作为对照组。应用Complior SP VP-1000 动脉硬化检测仪测 定颈- 股动脉脉搏波传导速度(C-FPWV)评估大动脉弹性。采用多元逐步线性回归分析性别、年龄、体质指数(BMI)、收缩压(SBP)、 舒张压(DBP)、总胆固醇(TC)、甘油三脂(TG)、空腹血糖(FPG)和尿酸(UA)等指标与高血压病患者大动脉弹性下降的影响因素。结 果:C-FPWV 平均值高血压组(1594±264cm/s)显著高于对照组(1216±231cm/s),两组差异有显著性意义(X2=31.659,P=0.00)。>40 岁各年龄段PWV 值上升程度,高血压组明显高于对照组(X2=18.954~36.924,P=0.00),两组PWV 值上升程度与年龄呈正相关。多 元逐步线性回归分析表明:BMI≥28kg/m2、SBP≥140mmHg、DBP≥90mmHg、TC>5.28±0.62 mmol/L、TG>1.68±0.64mmol/L 等 指标高血压组明显高于对照组(t=14.314~17.428, P<0.05)。在性别、UA 和FPG 等指标两组无明显差异(X2=6.368~13.618,P> 0.05)。结论:高血压病患者PWV 值上升程度显著高于非高血压者,BMI、SBP、TG、TC 是高血压病患者大动脉弹性下降的主要 影响因素。PWV 值可作为评价大动脉弹性的可靠指标。
英文摘要:
      Objective: To explore the evaluation and affect factor of pulse wave velocity (PWV) of large artery elasticity in hypertensive patients. Methods: Adopt method of full sample with 2178 cease of hypertensive patients and 2182 no-hypertension were antitheses group. Apply set out based by Complior SP VP-1000 Carotid-femoral PWV(C-FPWV),evaluation of importance index by way of large artery elasticity. Many cell expel drive linearity regress analyzed were C-FPWV, sex, age, BMI, SBP, DBP, TC, TG, FPG, UA and so no index. Results: C-FPWV in hypertension group(1594±264cm/s) was significantly higher than that in antitheses group (1216± 231cm/s)( X2=31.659,P=0.00). The apiece part of >40 age were hoist degree of PWV, hypertensive group was significantly higher than that in antitheses group (X2=18.954~36.924,P=0.00),C-FPWV were hoist degree in the two groups, PWV out of the way along with age add and that hoist. Make know many cell expel drive linearity regress analyzed in hypertensive group with BMI than that in 28 kg/m2, SBP than that in 140mmHg, DBP than that in 90mmHg, TC than that in 5.28±0.62mmol/L and TG than that in 1.68±0.64mmol/L were hypertension group was significantly higher than that in antitheses group (t=14.314~17.428, P<0.05). The sex, UA and FPG etc index had no significant difference in the two groups(X2=6.368~13.618,P>0.05). Conclusion: PWV in patients with hypertension was significantly higher than that in no-hypertension. BMI, SBP, TC and TG were hypertension patient of affect mostly factor main arterial spring depressed, evaluation of availability index large arterial elasticity for PWV.
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